So nice to read your message, Sundog.

"Even worse, in my case, I actually have a very nice life, yet I still manage to feel anxious and depressed (which makes me feel guilty and ungrateful to boot)".

I guess it really isn't about the external things. When the brain doesn't function properly, and produces a flood of miserable thoughts and emotions, it's hard to appreciate other circumstances and gifts.

"I do think it's neurochemistry to a large extent, since there isn't anything in my life situation to warrant the degree of anxiety I experience".

That was true for me at one time, too. I grew up in relatively fortunate circumstances in NY, my parents though dysfunctional in ways were loving and gave us a comfortable lifestyle. I earned a masters' degree at a well-known college, and had a career. I was attractive once, had men in my life, created art that was appreciated, but self-sabotage was etched into everything I did. I hope that didn't sound boastful. I didn't mean it that way.

"And I already do most of the "lifestyle" things that are recommended to boost mood (exercise, good diet, meditation, etc etc)"

Sometimes, you can do everything right, and still feel lousy.

"I'm so glad that you felt some relief yesterday by increasing your ADD meds. I really hope that boost lasts! Hugs to you! I'm glad you're here! I do find it comforting to talk to others who understand and I hope that helps you feel less alone too"

Thank you Sundog for your warmth and kindness. It means a lot to me to have found such compassion and comraderie in this community.

Hugs to you