my first time taking the seroquel..i told you i got knocked out...but i did take it again...i took it some time later...i took it at like 3am..after not sleeping for ...well.. a long time..anyways.. i was so worried to take it...shortly after maybe 45mins...i had a panic attack and made my husband take me to the hospital...so..i think your "thoughts" about it..before you take it have a huge impact on how it works.Something to think about anyways...i told my pdoc and i told her that while i realized it was a "thought" reaction..that i would not take it..i refused...that's when she gave me the abilify.