Oh yes. I've definitely had hypersexuality when manic or mixed. One at a time has always been my motto, but about 7 years ago, I had one partner after another after another with almost no time to recoup from the last. Thankfully I found the man I truly loved and was searching for, and have been together and completely faithful to him for the last 6.5 years. But, I did have a manic period in summer/fall of '09 and was so tempted to cheat with several guys. Don't know how I made it through other than knowing giving in would destroy my life and the man I love. Therapy helped. It's like you're a whole other person when you're UP. And the brain chemistry is telling you to mate with every guy with a pulse. :P Well, not every guy, but those who are convenient if not cute. Hope you're able to stay grounded and keep in touch with your friend if things get dicey.