I have been taking prilosec to combat the acid reflux that I get from taking depakote. For the last day or two, I have felt breakthrough reflux, but not too bad. Yesterday I had an upset stomach most of the afternoon. In the middle of the night I woke up twice with reflux so bad, I had to lean over the bed because I thought I was going to throw up. I managed to swallow (gross) it and I think I breathed a little in because I had to cough for a little while to clear my lungs. This used to happen before I took prilosec, but has been fine since taking it.

This morning I still feel a little refluxy, so I ate just a banana for breakfast.

Yuck. Does this mean I will have to go of Depakote? Reflux can't be good on a long term basis.