I gained about 40lbs from Seroquel a few years ago (after losing 80lbs 10 years prior) and it's so hard to take it off. I don't know how old you are Moose, but I'm 41 and no matter what i've done with diet and exercise my body is stuck at about 15 lls higher than i'd like it to be....i've been to diet doctors, nutritionists and a personal trainer, cut my calories as low as 900/day....it doesn't matter. So i do the best i can. Some of these meds make you so hungry and slow down your metabolism so you can't win - it's horrible. I'm sorry you're going through this but you are definitely not alone.