If Wellbutrin made you manic then maybe you are bi-polar ?
Have you tried mood stabilizers ? Do you drink or do other drugs that could interfere with your medication ? I'm in a similar position to you as i am on my 7th anti-depressant with none of the previous ones doing a single thing.
Parnate was meant to be the magic bullet for depression but that did nothing....... didn't change my diet or anything so maybe that effected it working. Got to laugh at doctors reaction when you tell them you drank alcohol or even ate cheese while on parnate.
I have tried effexor, cymbalta, lexapro, prozac, parnate, zoloft, and now on paxil.
Oh yeah and i'm on seroquel for sleep.
If they had meds that could make me numb and just content to stare at the wall all day i would take it. Just take this pain away...