I just wrote a post about feeling numb and lifeless right now today. However, I've been on Zoloft and Depakote for a long time - like 12 years - and except for the occasional few days of depression here and there, functioned "normally."

Prior to Zoloft, I was first put on Prozac and I didn't respond well to that, thus the change to Zoloft.

Now I'm in the midst of a depressive episode to the degree that I have not experienced since 1993. Why the brain chemicals do what, when, is totally mystifying to me.

Anyway - (starting to ramble) - I also would agree with talking to your pdoc - there are a lot of new anti-depressants even since I began on Zoloft.

Good luck with that and hope we both start feeling "alive" again soon!