Have to add my 2 cents worth here.....I am taking seroquel again for the PTSD that came after living through a tough trauma last year when my Mother was dying of cancer (at this exact time of year). Several years ago I had been prescribed seroquel for depression, & took it on & off....never consistant....only when I felt like I was having horrible anxiety attacks while trying to deal with the depression that just wouldn't go away. I had some left over from the prescription & when I was living through the trauma last year my pdoc tried me on just an antianxitey med which had NO effect at all. I was having a horrible time trying to deal with the police & the situation I ended up in....while staying with my Mother 24/7 in the hospital to make sure that no one would get to her to try to make sure she didn't say anything about the ID theft. She kept me awake continually trying to ease her pain & do things that the nurses were to busy for. I was getting so exhausted & was at the point I couldn't eat or drink anything & keep it down. During that time, I ended up being hospitalized for the anorexia condition I was having. On the few days I went home for my mothers funeral, I located the seroquel I had left over. It seemed to ease the insomnia caused by the horrible nightmares & flashbacks that kept haunting me so I suggested it to my pdoc & we worked on a dosage that was helpful. I started with a low dose & it just wasn't enough.....so increased it to 300/400mg at night. It really knocked me out for the sleep I needed so bad. During the day when I was experiencing the "depersonalization" symptoms, I would take a lower dose (25mg). It does ease the anxiety attacks well.

Even though it is supposed to have an effect on weight, my weight was so low & I wasn't able to get food down....so it had no effect on my weight. Unfortunately, I didn't realize how bad it would be, living through the year anniversary of it all. I have been taking the night dosage hoping that it would knock me out so well that nothing could get into my mind.....unfortunately, it isn't working well & the nightmares & flashback memories are as if I am living through it again. Because of this, my mind seems to be not allowing me to sleep even with the large dose of the seroquel. When I take it, my transition from sleep to wake everyday is when my mind takes over while in that drowsy state.

I don't like the feeling I have the next morning.....feeling dizzy & sometimes not even knowing where I am. The seroquel isn't helping as much as I had hoped right now....but I still think I am better off than I would be without it.

So the answer to your question is yes, I am taking seroquel for PTSD symptoms with some success. I hope you find that it helps too.......I do like being able to have a med knock me out so well at night.....but the next morning feelings when I need to be able to function is difficult to live with.

Debbie