I have been alone pretty much all of my life. Even when I am in the midst of a crowd, I feel no connection. There are many reasons for my present circumstances, none important to this discussion.
The overarching downside of my existence is not having people to talk to. It is not so much the talking per se; rather, it is not having others signal how well I am by how they react to what I say. Seeking the approval of others is not the goal. I do know only having my thoughts cavorting through the caverns of my mind is problematical. Talking to others gives me some idea just how problematical.
http://psychcentral.com/lib/2006/are-you-lonely/all/1/
http://gmj.gallup.com/content/126884...?version=print
http://www.uic.edu/depts/wellctr/dimen.shtml