Oh.......let me weigh in here. I'm BP1 through the roof. I'm on Lamictal now ( the Lithium was absolutely intolerable). I'm on Prozac by day........Seroquel (150mgs, down from the 300mgs I was recently on) and Ambien at night. I started with Abilify but stopped as soon as I recognized the symptoms of tardive dyskenesia. Too late and not reversible. I had to educate my pdoc because it's so rare, according to what I've read........but I am in the highest risk group for it due to gender and age. I'm worsening overall not because of meds, but due to the severity of my illness. I'm very drugged at night but I welcome it.....an escape from my reality. Well, that was the long answer to your question. There is no doubt, at least for me,that I'll be on meds for the rest of my life. Bleck. Sorry. What I've been holding in so long is starting to seep out. All well wishes to you.........grey