I will be 46 on thursday and havent had my friend since december, although it feels as if i could get it any second, very crampy, sore chest, cranky and tired. I swear by evening primrose oil, i take 2 a day and they have taken away the horrible hot flashes i was getting in January. My mom was 44 and she said her period was irregular for 6 years. I think we are all different. Hang in there, try the natural herbs, they seem to calm the symptoms... for now! hahaha take care, i know how you feel!!