I was just dx with Borderline Personality Disorder and Bipolar 1 a few months ago. I've been on Cymbalta (120 mg a day) for the past 7 years for my chronic depression. It has saved my life as the other anti-d's I tried the for the 3 years prior didn't deal with my anxiety. After being newly dx I had wanted to "meet the real me" and took myself off all my meds. NOT a good idea quittin the Cymbalta cold turkey!! But i see my T twice a week and am back on my 120 mg of Cymbalta... I am NOT a nice person without it! I don't see my phyciatrist until the end of May so any new "cocktail" is out of the question until then . I've found that my suicidal tendancies (Borderline related) are severe when not on Cymbalta. Thank you for this thread, I have been wondering what has worked for others and this is the first I've see anyone mention Cymablta!