The emerging consensus is that anti-d's should not be used for bipolar; the author of the Bipolar Handbook, Wes Burgess, was a little ahead of the curve on that in 2006 when he wrote the book.

However, it's very difficult to elevate mood without them. When I've tried to go off Effexor, my mood has plunged even tho i'm on lamictal and lithium. But it's probably true that anti-d's make bp worse over the long run. No easy answers.