The irritability can be a sign of your depression. I learned that the hard way, myself. Thought I was just being a witch, then got upset when I was in the psych ward with one of the techs who said something jokingly to me that I took as demeaning (he was being lazy too). I was so infuriated with him, that I had an epiphany--all those other times when I was *****y, it was my depression talking! Now that I am properly medicated for my depression and getting some counseling too, I'm back to being "Sweet Susie" like I was in my non-depressed times of my life.
Are you getting treatment for depression? Meds? Counseling? Might be that both are in order. Let us know how things are going.

