hmm...

My suggestion is you pick the job or opportunity for work that you find satisfying. Sure, staying home also sounds like a good option... But would you feel fulfilled?
Could you apply your time in a way that would bring fulfillment in leaving the work force? Having too much free time to think about things, is just as bad or worse than having too much to do.

Best advice is whatever path you choose; give yourself some TLC and develop a strategy to improve or overcome the symptoms. I found an excellent book recently that provides six steps in curing depression and people have also reported it's excellent for anxiety.

Basically the premise is that modern life, is way out of synch with how we humans have evolved over time.

1. 1000 to 2000 miligrams of Omega 3 per day in the form of fish oil. Recent dietary analysis has determined that people are getting way too much Omega 6, where we evolved on the basis of a 1 to 1 ration of Omega 3 to Omega 6. Addressing the imbalance provides the necessary fuel for our brains to function well.

2. Making the commitment to a regular sleeping schedule getting 9 and one half to a minimum of 7 per night. Humans used to sleep ten hours per day and we average only 6.7 now.

3. Regular exercise, whether it's just walking, or riding a bike.

4. Monitoring one's own thought patterns, and stopping "rumination" in it's tracks. By refocusing on an activity or something productive. Or turning thoughts to something more positive...

5. Humans are social creatures; make sure you're tending your garden of relationships. Family, friends, co-workers, community etc.

6. Sunlight! there is no substitute we need some daily.

When you say mania; the above elements will be very helpful in maintaining a more comfortable even. However, mood stabalizing pharma options are still often needed for individuals who experience life through the bipolar lens.

The above however are very effective and healthy steps for anyone in achieving work, life and health balance. They're more effective long term for depression vs. medication for most people. Reduce anxiety, and work very well in helping individuals who occassionally struggle to fit into the modern would, just being...find more stability in balancing out.

So either way, or however you choose to apply your time. The above will definately help keep life more harmoniously balanced.