Seroquel 25mg knocked me out for 36 hours at a time. I took it only when I was manic and out of control, or had hallucinations. As the Seroquel took effect, I experienced a deep numbing heaviness that felt like a heavy black blanket covered in sticky tar smothering the life out of my soul.
I have been containing mania with Lithium since then, and do everything I can to avoid antipsychotics, even if it means living with some strange experiences.