Hi Melissa,

Sorry to hear that you're having a rough time right now. I am also on Wellbutrin and it has not triggered mania or cycling. I have had awful manic/cycling reactions to SSRI and tricyclic antidepressants. Paxil, Zoloft, citalopram, Lexapro, etc, really send me spinning. Amitryptiline really ramped me up as well. But not the Wellbutrin.

You didn't mention what other meds, if any, you are taking. I have never taken Wellbutrin without a mood stabilizer, so I cannot attest as to whether or not it would trigger cycling without one. SSRIs, on the other hand, will send me off even with a mood stabilizer on board.

It's a delicate balance.

I would certainly let your pdoc know what's going on as soon as you can. The most important thing is your safety. Try to be gentle with yourself while you're going through all this.