I never tried that medications but some antidepressants/anti-anxiety meds do help me with my dissociation problems. It doesnt help as in stopping the disociation.

the way it works - The meds help me to feel less anxiety, less anxiety for me means less depersonalization from things that trigger my anxiety.

There is no medication to combat dissociating per se. but dissociation can be triggered by trauma, depression, anxiety and medication so doctors treat those things to alleviate dissociation problems.

here in the USA naltrexone is primarily used to treat drug and alcohol abuse/dependancy. the way it works is it stops the cravings for alcohol and drugs. should the person choose to use drugs and alcohol it makes them extremely sick so they dont want to drink or use drugs.

this medication isnt used alone because its only used for a short time, therefore people on this medication in the usa also go through therapy / classes to help them better manage their problems.

for some people this drug like any other medication does cause the same symptoms of depersonalization such as numbness, disconnection to the world around them, feeling hung over, slow motioned, like the world is not real.