Sounds like the depression is filling your head with all these negative self-thoughts and making you want to isolate. Humans are social creatures and as much as we try to deny it, we need people. Have you tried interacting with people? I don't know very much about you, but you could always join a group or club, go for a walk, hang out at a coffee shop, volunteer somewhere. What do you enjoy doing? If you find an activity that you enjoy, chances are you will meet people with similar interests.