I'm sorry to hear that you've had such a difficult time despite multiple med trials. Not sure if you've tried Seroquel, but they've found it helpful for depression - both unipolar and bipolar. It could be used with a traditional antidepressant and will probably help you sleep.

Here's a link to an article about it : http://www.webmd.com/bipolar-disorde...lar-depression

I hope you find some relief soon.