Quote:
Originally Posted by mgran
Okay, I'm sorry. I guess you're all right, and I have been looking at this from a fortunate point of view. I'm more lucky than anything that the meds (thus far) have worked.
Buddha, you say it's difficult to come off the meds after more than six months of use... Could I ask if you have any evidence of addiction to meds? I must admit, that's one area I've worried about a bit. And like others I have had side effects, mainly somnolence (particularly acute in the mornings) and weight gain, which I'm slowly chipping away at.
And again, I apologise if my previous gung ho post offended or upset anyone. As I say, you're correct, I've been lucky.
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I wouldn't call it addiction. There's some evidence that these drugs modify the brain after long term use. The brain plasticity is well know. If you block a receptor (dopamine or serotonin) then the brain will produce more of those receptors.
http://www.ncbi.nlm.nih.gov/pubmed/11057521
http://www.ncbi.nlm.nih.gov/pubmed/21300943
http://www.ncbi.nlm.nih.gov/pubmed/12418933
http://www.ncbi.nlm.nih.gov/pubmed/11163778
http://www.ncbi.nlm.nih.gov/pubmed/10593448
http://www.ncbi.nlm.nih.gov/pubmed/10720329
http://goo.gl/TlT2l