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Old May 26, 2011, 07:33 AM
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dragonfly2 dragonfly2 is offline
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Member Since: Mar 2011
Location: New England
Posts: 873
Very interesting topic. I have definitely experienced triggering of both mania and rapid cycling on antidepressants - both tricyclics (amitriptyline, nortriptyline, desipramine, etc) and SSRIs. I already rapid cycle, but the antidepressants definitely make it worse, and the intense cycling continued for almost a year even after I stopped the medicine. This is even with the use of a mood stabilizer.

I found a couple of good articles on the subject. The first one is from a popular bipolar blogger who references a number of different studies. The second one is a very comprehensive discussion on the subject, with multiple articles attached.

http://www.mcmanweb.com/treating_bip...epression.html

http://cnsdiseases.com/antidepressan...polar-disorder
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I've been scattered I've been shattered
I've been knocked out of the race
But I'll get better
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~Sting, Lithium Sunset


Thanks for this!
Tsunamisurfer