I did some research this morning and came across a wealth of information. Many people who take Depakote to control seizures start having siezures again when changed to a generic version. When changed back to the brand name, the seizures disappear.

I can well imagine that this lack of effectiveness with generics can cause the same issues with those taking it to control BPD. I know my wife has been very stable until changed to the generic about two months ago. Now, she is barely holding on. The meds are the only thing that has changed.