tell your friend NOT to do it. unless shes looking to spend some serious time in the ER. i absolutely do not advocate the use of street drugs, but i do know that certain illegal substances, when taken in combo with prescription drugs, are rendered SOMEWHAT and i emphasize the somewhat less harmless than when taken alone. this is not one of them. i know you cant change someones mind once its made up, but you might want to do your best to convince your friend that shes risking her life.