okay ... what if the prozac was reduced for a week then stopped for a week before the occasion of the party? would two weeks be enough to get it out of the system?

i think my friend is pretty set on going out and partying as normal (well before they started meds).

i have known a friend who took the combo and nothing bad happened, they just felt a dulled-down effect of the drug - not nearly as euphoric.

Would the serotonergic syndrome have anything to do with the dosage of prozac and the amount of E taken?

thanks for the responses, very very helpful.