I've been feeling very depressed (even more than usual) despite the fact that I'm taking Wellbutrin (300 mg/day). I've asked my psychiatrist to up my dose, but he refuses despite the fact that I've had no adverse side effects from Wellbutrin. I've tried many other meds-a whole host of SSRIs, SNRIs-but only Wellbutrin actually helps me without all the usual side effects.

Additionally, I try to exercise several times a week; eat a very healthy diet; I've gone to yoga classes recently, I try to take downtime when I can, which isn't often, but still.

So my question is: how come I still feel like I'm spiraling down into despair, and loneliness, headed back into a major depression? I'm starting to get that dead, detached feeling every morning when I wake up. Has anyone had experiences where they feel like they're overwhelming their meds ability to work, and what do you do about it?

I know that some of this is due to my living circumstances: I'm a senior in a private, very demanding college that I quit my job for in 2008 to attend (I'm 31-not a typical student), bad off financially, in a relationship that I'm not certain about at all (and can't leave, because of the aforementioned finances). Additionally, I have 2 little boys. I don't have any family or friends that I can turn to for help, or go live with to get out of this situation, as they've always tried to be harmful rather than helpful. But I can't do anything about this situation right now-I feel like my only hope is meds.

I'd appreciate hearing from anyone with an experience like mine, or helpful ideas.