I was on Lamictal years ago and it helped with the depression but made my mania stronger. The only side effect I had was dry mouth. I was bumped up to 300mg and was frustrated with my p-doc, so I went off and didn't take anything else for a long time.

I am now on it again and it worked well with Seroquel, but doesn't seem to be doing anything now that I am off Seroquel. I think I simply need to get up to a higher dose and find something that plays nice with it and my body. Just as last time, my only side effect is dry mouth.

I think, for Bipolar, it is a good option if used with something else or if you are depressed more than manic (at least that's what I was told). I will keep taking it and see how it works when I bump up the dose.