hello, I take B complex vitamins and find that if I miss a few days I feel worse. also when I was taking Prozac I found it helped to take some Melatonin before bed (it will make you very sleepy, and I only take 1mg, or a half of a 3mg tablet because 1mg is hard to find). I switched to Celexa about a month ago and that makes me sleepy so I havent taken the Melatonin while taking that. but I read somewhere that there is a new antidepressant being developed that will include Melatonin in the formulation.