Quote:
Originally Posted by Lichenme
I have gained some weight since being on the risperdal and it has been hard to get it off, even with eating right. I also thought it was only going to be a temporary thing and it has been 20months now, I don't consider this temporary. The reason why I was put on it was for bipolar rapid cycling back in 11/2009. I have been stable since 2/2010 with small med changes. I think that I may be missing my highs a little too.  |
I should've caught it sooner so my apologies. I looked and prozac and risperdal have an adversive drug-drug interaction on a specific enzyme (CYP2D6). Unfortunately, Toprol XL also uses the same enzyme and is known to interact with prozac in a way that yields greater amounts of Toprol XL's active metabolites than intended. In other words, the interaction causes more Toprol XL to be processed in your body than intended. The overall result would be a greater decrease in blood pressure than desired, so depending how the shadows appear, they could be a product of decreased blood flow but probably wouldn't result in the other symptoms.
I'm a little confused on something. When you mention "highs", do you mean manic or hypomanic symptoms, or simply feeling positive or euphoric drug-like highs? I get the feeling you mean manic or hypomanic highs but I just want to be sure.
Earlier you said you were on risperidone for 20 months, how long have you been weaning yourself off it? Unfortunately, some people do experience weight gain and it doesn't stop the longer you stay on it, however, risperidone probably wouldn't contribute to a reservoir.