I'm taking 350mg a day ,my doc. gradually put me on higher dose , but I started to have tremors ( shaking ) end memory loss earlier , probably around your dose. For the memory loss he said it's " part of the depression ". I haven't gained weight in the beginning , end actually I felt great , because I didn't had constipation , which I had with other pills , I had a bit of loss of appetite also ...........but now..........I don't want to weigh myself , I'm so upset , and down about my weightgain. I guess now I'll be depressed about gaining weight and than I have to take more pills to feel better. Is this what they call a vicious circle ? Is this what the pharmacutical companies want us to do ?