I have to say that I had problems with Wellbutrin, but those were easily solved by the various ED drugs. It got much worse after adding Effexor, but the problems disappeared after discontinuing both. I have not taken topiramate, but I have had no problems with my current cocktail, which includes lithium, Lamictal and trazodone.

Wellbutrin was better than the SSRI's I took before, but I don't feel that I have really felt "normal" until the past few months.

Now, if I could just find someone for human testing....

DJ