I get that feeling at least once a day. It's tiring, annoying, defeating, painful...I just cry. That's the only way to get my frustration out without causing harm to myself or others. I self-medicate also, but I'm not going there.
Annnnywho....You want to run, but there's nowhere to go and no way to get there (In MY case anyway). I totally feel your pain babe, that's all I can say.