It obviously has always affected you personally and you always have the right to open your big fat mouth in that situation You are responsible for your environment and if he is dissing your stuff and the professor and making it hard to do your work comfortably then. . .

Just keep it about you, instead of him. You are allowed to think whatever you like about a person and let anyone else who's listening hear your point of view if they are in a position to do something about it. Just say things along the lines of "I get angry and uncomfortable when he disses you and my work, when he doesn't know the first thing about it" and, "He interrupts me when I am working and he is not and has not taken the hint to leave me alone so I can get my work done".