Some of the newer antipsychotics have very unpleasant side effects like oversedation, no effect, or extreme agitation. They are pushed by the drug companies , but may not be the right fit for a particular person. Then they try different ones to see which one works. It doesn't make for a very good treatment plan. Perphenazine is an older antipsychotic which works well and doesn't cost alot. Perhaps the PDocs should reevaluate the older effective treatments too.