I have taken both meds. Wellbutrin was very dangerous for me. It turned me into a lunatic. I was unable to control my anger and would just sit around thinking of things that got me even more angry. I had to isolate myself from family and friends just to not hurt anyone's feelings or physical being. I went to my doc that prescribed it and asked for something to bring me down off of the stuff but he treated me as a drug user who was just looking for a quick fix.

Topomax on the other hand had no ill effects on me. I just didn't feel any different. My doc was giving me many medications that were prone to weight gain and he stated that Topomax would counteract that. It didn't. Ended up gaining 60 pounds.

Best of luck to you.