I have the same diagnosis of rapid cycling mixed bipolar. I too have had a hard time stabilizing. I didn't see depakote on your list of meds. I had a significant improvement when I started it. I am still not stable, but I see an improvement. I take depakote, prozac, wellbutrin, trazodone, propanolol, and risperdone at the moment. I will be getting off risperdone soon because side effects. I hope you find some relief soon.