After researching T3 and it's efficacy for relief of bipolar depression I ran it by my P-doc and after the appropriate thyroid tests he agreed to try it. I will start at 25 mcg. While my T3 was within the "normal" range, the studies have shown that bumping T3 up to what is considered higher than the norm successfully relieved treatment resistant BP depression. I am optimistic about this "trial" and happy that he is willing to prescribe it.

I asked if any of his other BP patients were on it and they're not, (so I'm the guinea pig), but since I did the research and proposed it I'm OK with that. I am also on Lamictal (Lamotrigine) 200 mgs. which has subtly worked it's magic on my depression as it was titrated up. I've had relief from the depression but I am still lethargic.

I've run the gamut of SSRI's and they weren't effective for me. I am also thankful for the "weight neutral" profile of Lamictal since I gained 20 lbs. over 6 months from comfort eating, depression, and a back injury. He suggested the T3 effect might be a "placebo effect" but I'll be the judge of that. They are doing clinical trials of T3 for BP at a major medical center in NY, but based on the studies so far I'm going for it.

If anyone here has tried T3 I'd appreciate feedback. I'll give an update as to wheter it works for me (or not)...