I used to be on Depakote that did nothing for BP, caused severe weight gain, messed up bloodwork BUT completely erased my migraines. I was taken off Depakote, but now with my primary doctor we are considering restarting it on a low dose sufficient to prevent migraines, as migraines have gotten the better of me recently. 3 attacks per week, not good. Depakote is FDA approved for migraine prevention and the dosage for that purpose is lower than for BP.

So my question is for people who are on full Bipolar doses: did you notice new side effects are you titrated up? Say weight gain started after a certain dose only?

Thanks.