Has anyone been on seroquel and tried to ween themselves off of it before? I have been taking mg. of it at night to help me sleep for many months now. being my stubborn self, I tried taking myself off of it thinking I may not need it anymore. One night, I took themg, the next 3 nights I took only mg. 2 or 3 days later, I crashed. I became dangerously depressed and that was my first mood swing in months. My question is, has anyone experienced such a drastic mood change when weaning themselves off of seroquel? Thanks all for listening.