I am really hoping the lactimal helps with my irritability and agitation. My pdoc has me on 300 mg of Seroquel at night. It really helps with my sleep, but hasn't done a thing for my daytime symptoms. I am going to be hopeful...it just sucks that it takes so long to get up to the right dose...I want something to work right now! lol I really need some stability with my moods. I read at CrazyMeds that Lactimal is hands down the best treatment to bipolar ii, so here's hoping.