i have both irritable bowel syndrome (IBS) and heart disease. my MD insisted that i go back on aspirin therapy and i recently resumed it. i had stopped several years ago because of side effects. this time, i tried taking the aspirin at a different time from fish oil because the two did not mix well (one is acidic and the other is fat, resulting in acid reflux). but, i'm still having some very bad gastrointestinal side effects. and, i am always cold (a result, i think, of my blood being thinner). trouble is, i don't tolerate statins either. today, i decided to stop taking the aspirin and to make an MD appointment. i am feeling very frustrated.