Have you tried taking the 'enteric coated aspirin' - this is easier on the stomach. I used to get horrible acid reflux and was on Nexium for several years until I suspected it blocked the B vitamins and I was right. I now take Ester C - its more expensive but its a buffered vitamin C which balances the acid in your stomach. When I do get acid reflux - I also use this natural remedy - swallow 2 tblsps of lemon juice then drink some water. You can also swallow some fiber capsules and this will absorb some of the acid. Laying on your left side also helps. Can you tolerate yogurt or acidolpholis supplements - friendly bacteria will help the IBS symptoms. Try the Ester C - its wonderful for the stomach.