Yes, I isolate. When I'm depressed, I'll do almost anything to spend 8 hours or so all alone, just hanging out in my sweats at home watching t.v. and having coffee all day. Sometimes I sleep on the sofa after a good cry and then wake up and have coffee again. LOL It's actually physically painful when I'm depressed to be around people. But I have to watch myself, too - I don't want to isolate so much that I start having suicidal thoughts again. That stuff was beyond frightening!