Yes this can cause liver problems/failure especially when combined with alcohol. It can also cause death - the Oxycodone combined with the alcohol slows down the involuntary nervous system ....primarily the heart and breathing.... causing the person to die in their sleep. The person wouldn't even be trying to end their lives and won't be in control of dying. Even simple acetaminophen can cause liver failure if taken over an extended time especially when combined with alcohol. My BIL took it regularly and took a little to many and died....my brother was hooked on it and he ended his life. I'm not lecturing but just giving the facts and my own family experience. Here's a quote from a link on the dangers of Oxycodone:

"Oxycodone is the deadliest drug in the U.S.: it causes more deaths than cocaine and heroin combined".