For a MS program, salukigirl is right, it matters more what they say than who says it. I'd be a bit wary about having a therapist write a letter, though - that would be viewed as a little odd. I asked prior job supervisors to write me recommendations for my MS program, since I was too long out of undergrad for my profs to remember me (and I didn't do that well in undergrad anyway...) It can help for you to give them a paragraph that you write saying why you're a good candidate for the program, then your recommenders know what to say. Also, the admissions committee are unlikely to be concerned about your job history or gaps in it; usually there are hundreds of applications to review, so a few heuristics are used to cut the pool down to a reasonable size for human review, and there are still so many applications that really close scrutiny is not so common.

However, if you're applying for a PhD program, then it matters a lot who writes your letters! That's a whole different thing. All PhD programs are selective, and most are very, very selective; we accept under 10% of our applicants each year, and the constraints on admissions are very complicated.