jshect, With being bi-polar we all have to be very carefull about taking anti-depresants because they can throw you off balance. Kinda like tetter totter. If you treat the manic whithout the depress it most likely will throw they other up in the air. I would almost think the agression could be from treating the depression has given you lots of energy thus throwing you a bit manic. Manic can manifest in several different ways (high, agression, emotional). Talk to you doctor about how you feeling. Good luck wish you the best.