Hello, Élan Vital!

I do not have a well-informed opinion regarding this question. I lack the background and intelligence. Nevertheless, I can say that I experience depression as a biopsychosocial tangle. My treatment has involved psychiatrists, psychologists, neurologists, a neuropsychologist, general practitioners, internal medicine doctors, pulmonologists (as sleep specialists), and gastroenterologists.

Yes, for me anyway, it's a multi-headed monster.