I think bpdruins is onto something with the residual effects for some people, which of course only reinforces the "don't need them" thing. Till the symptoms do come back, sometimes with a vengence, and one is left scrambling. (Guess who's had to scramble?)

I've never forgotten more than a dose or day (which is shocking, because sooo bad with any other sort of routine), pretty much all pre-pillbox. I do get the wanting to go off sometimes for the oh-so-classic "feeling better so must not need them" or the "feeling so crap, what is the point anyway?" thing. But as soon as I get it to a too low a dosage point, let alone go off, I'm very quickly reminded why I'm on them. (And still conveniently "forget"/"not believe" this every time I'm tempted. And yes, despite abundant evidence, temptation still comes.)

Hear you on the up can be total b**** and rage land. I go both ways (ie. goes that or goes euphoric. Or both.). When it's the beyond irritable mode, it's really awful, and has produced many of my most regretted actions. For sure. Mortifiying even. It's a good incentive/reminder that I really shouldn't go off, because I don't want to go back to being so out of control in such a negative destructive way, and the meds have helped with that.

As for remembering, the day of week pillbox is right by my bedside where my phone (and therefore clock) is. Very helpful. For pm, my phone is set with the alarm to go off the same time every night. Because those are the most likely to be forgotten, as I'm not near the box and have no sort of routine at night mostly in that hours can be pretty all over the place.