One Perspective: Your husband probably cannot handle right now all you want to tell him about how you are feeling. The words "depression" and "anxiety" carry all sorts of varied and mostly negative, even adversarial meanings for people. You might be able to skirt the guilt problem by stressing the biological angle. You are suffering from an illness that interferes with brain function and it affects your mood and emotions. If you had a broken leg, that would affect your walking. It's not his "fault," he cannot "fix" it and it's not his responsibility to fix it. (This not being the other's responsibility to fix depression is something I stressed early on with my spouse.) At the very most he might be able to make you feel a little more comfortable, but that's it.

Please keep posting, Curlydee.

Edit: Even if your husband can grasp something of what you are going through, it may nevertheless greatly unsettle him that he's facing something he cannot control or influence.