So far no problems with munchies but I am really, really groggy in the mornings since I started taking it. I'm on 25 mg and was supposed to up it to 50 mg last night but I'm waiting until Friday night. I have to get my oldest to school by 7:45 and I'm afraid I'll sleep through the alarm. My husband said he was very surprised by how well I did yesterday despite only getting 2 hours of sleep the night before. He attributed it to the Seroquel. However, I got 4 hours of sleep last night and the bipolar is pretty bad today. I'm cycling like crazy and just had to take an Ativan. My psych doctor said the Seroquel will hopefully keep me from hallucinating and hopefully control everything better. We'll see, although I tend to think if I'm not getting much in the way of sleep it's not going to matter what I'm on. I'm going to rapid cycle and will have to keep the Ativan around to help me keep things under control on those days.